​The Premier League's relentless schedule continues as we head into Gameweek 6, where squads will once again be tested in a series of high-stakes clashes. This week's standout fixture sees a defensively better Manchester United host a resurgent Tottenham Hotspur, who have found form under Ange Postecoglou. The stakes are high for both sides as United looks to maintain their defensive stability, while Spurs aim to extend their winning form. In the mid-table battles, Chelsea, riding high after back-to-back victories, take on Brighton, who remain unbeaten so far this season. Meanwhile, Everton and Crystal Palace both seek their first wins of the campaign in what could be a decisive clash at Goodison Park.

Key Takeaways from the Gameweek 5

Stone's last minute equalizer. Source:premierleague.com

In a fiercely contested top-of-the-table clash, Manchester City and Arsenal played out a thrilling 2-2 draw, with tempers flaring right from the kickoff. Meanwhile, Aston Villa turned around a sluggish first half against Wolverhampton to secure a convincing 3-1 victory, showcasing the depth of their squad. Spurs capitalized on their midweek EFL Cup victory to carry momentum into the weekend, defeating Brentford 3-1 in a dominant display.

Elsewhere, Manchester United's defense held firm in a chaotic 0-0 draw against Crystal Palace, earning their third clean sheet of the season. Chelsea exploited West Ham's tactical errors to claim a comprehensive 3-0 win, while Raul Jimenez's return to form helped Fulham secure a 3-1 victory over Newcastle. Lastly, Nottingham Forest's unbeaten start continued with a 2-2 draw against Brighton, as Everton showed signs of improvement in their 1-1 stalemate with Leicester City.

Players to watch out for Gameweek 6

With the packed fixture list and the demands of European and domestic competitions, the risk of injuries and suspensions has become a growing concern for managers. Fantasy managers will need to keep a close eye on these developments to avoid costly lineup errors. Here’s a look at the key players who will miss this round of action:

Notable Absences

Manchester City faces a massive setback as Rodri has been ruled out for the whole season due to a knee ligament injury, leaving a void in their midfield. Kevin De Bruyne will also be unavailable at least next gameweek. Meanwhile, Nottingham Forest will be without Morgan Gibbs-White, suspended after his red card against Brighton. Edson Alvarez (West Ham United) also serves a suspension following his dismissal in the EFL Cup defeat to Liverpool. Southampton’s defensive troubles continue as Jack Stephens remains suspended until Matchweek 7 after his red card against Manchester United. Brighton's attack will miss the presence of Joao Pedro due to injury, and Newcastle United’s Alexander Isak remains doubtful for the crucial clash against Manchester City as he continues to nurse a toe problem. David Raya has been a doubtful start for the next gameweek and can only be confirmed after the start of the gameweek.

Forwards

Raul Jimenez, Fulham
Raúl Jiménez performing great for Fulham. Source: goal.com

a. Luis Díaz (Liverpool) is a top pick for fantasy managers. With 5 goals and an assist already this season, the Colombian winger is thriving under Liverpool’s new attacking system. He netted twice in the last game and will be keen to exploit a shaky Wolverhampton defense that has yet to secure a win this season. Díaz’s explosive pace and finishing could see him rack up points in Gameweek 6.

b. Bryan Mbeumo (Brentford) continues to impress with four goals in five matches. His powerful display against Tottenham last week showcased his growing confidence and goal-scoring ability. Brentford will be counting on Mbeumo to lead their attack once more as they face West Ham United, making him a standout option for fantasy managers looking for an in-form forward.

Tip: For 11.2 credits (225.4 points), Raúl Jiménez (Fulham) is a smart and cost-effective choice for fantasy managers. His early goal in Fulham’s last match was his eighth in his last nine Premier League starts, a remarkable record that has largely flown under the radar. With Fulham's upcoming fixture against Nottingham Forest, he is a forward worth considering for this gameweek.

Midfielders

Youri Tielemans celebrates goal

Youri Tielemans. Source: bbc.com

a. Bernardo Silva (Manchester City) is set to take on a more prominent role in the season-long absence of Rodri and the temporary absence of KDB. With two assists already this season, Silva will be key to breaking down Newcastle United’s tough defense. His creativity and ability to control the tempo will be essential for City’s success in this crucial matchup. Fantasy managers can expect him to be a major contributor to City’s attack this season.

b. Lewis Cook (Bournemouth) has shown flashes of his defensive prowess despite Bournemouth's struggles. After a tough loss to Liverpool, Cook will be looking to bounce back in the upcoming clash against Southampton, a team also struggling at the bottom of the table. His ability to disrupt play and contribute to the midfield battle will be vital in turning Bournemouth’s fortunes around.

Tip: For 9.6 credits (328.2 points), Youri Tielemans (Aston Villa) is a standout pick for fantasy managers. Tielemans has already contributed two assists and is playing a pivotal role in Aston Villa’s strong start to the season. Facing newly promoted Ipswich Town in the next match, Tielemans is expected to create more goal-scoring opportunities, making him a high-value midfield option for Gameweek 6.

Defenders

Jan Paul van Hecke provided the assist for Jack Hinshelwood's goal against Nottingham Forest (Photo by Steve Bardens/Getty Images)
Jan Paul van Hecke provided the assist for Jack Hinshelwood's goal against Nottingham Forest (Photo by Steve Bardens/Getty Images)

a. Pedro Porro (Tottenham Hotspurs) has been a standout crosser, delivering the most accurate crosses from open play (8) in the Premier League so far. His ability to create chances will be crucial as Spurs look to penetrate Manchester United’s solid defense. Porro’s knack for stepping up in high-pressure situations could be the key to turning this tough away fixture into a valuable win for Tottenham.

b. Noussair Mazraoui (Manchester United) has quickly settled into United’s defensive lineup, contributing to three clean sheets and registering an assist. As they face a potent Tottenham attack, Mazraoui’s defensive positioning and timely tackles will be pivotal to containing Spurs’ threats and helping United secure another solid defensive performance.

Tip: For 5.6 credits (322.6 points), Jan Paul van Hecke (Brighton) is an excellent pick for fantasy managers looking for value. With two clean sheets and an assist to his name, Van Hecke’s dual threat in defense and offense makes him a valuable asset as Brighton aims to maintain their unbeaten run this season against a strong Chelsea side.

Goalkeepers

Dean Henderson of Crystal Palace

Dean Henderson Source: bbc.com

a. Alisson (Liverpool) is set to return against Wolves after missing the previous match. The Brazilian shot-stopper had been in top form with 3 clean sheets in his 4 Premier League starts this season. Liverpool will be relying on Alisson’s consistency and sharp reflexes to help them regain their defensive solidity.

b. Nick Pope (Newcastle United) faces a daunting challenge against table-toppers Manchester City. With City’s attacking firepower, Pope’s shot-stopping abilities will be crucial for Newcastle to have any hope of securing a positive result. As one of the best-performing goalkeepers this season, he will need to deliver a standout performance to keep his team in the game.

Tip: For 4.7 credits (223.8 points), Dean Henderson (Crystal Palace) offers great value. After a solid display and clean sheet against Manchester United last week, Henderson is a strong candidate to secure another clean sheet as Crystal Palace takes on a struggling Everton side.

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